
Tarlatamab The Promising Immunotherapy On Its Way From The Lab To
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Oct 20, 2023 · Tarlatamab, a bispecific T-cell engager immunotherapy targeting delta-like ligand 3 and CD3, showed promising antitumor activity in a phase 1 trial in patients with previously treated small-cell...
Nov 20, 2025 · The FDA has granted full approval to tarlatamab, a targeted immunotherapy drug for treating adults with advanced small cell lung cancer (SCLC) that that has spread after platinum-based …
Tarlatamab, sold under the brand name Imdelltra, is an anti-cancer medication used for the treatment of extensive-stage small cell lung cancer. [5] It is a bispecific T-cell engager that binds delta-like ligand 3 …
May 16, 2024 · IMDELLTRA™ (tarlatamab-dlle) is indicated for the treatment of adult patients with extensive-stage small cell lung cancer (ES-SCLC) with disease progression on or after platinum-based …
Jul 12, 2024 · Tarlatamab is used to treat non-small cell lung cancer in adults who are no longer responding to platinum-based chemotherapy. Tarlatamab is used when the cancer has progressed or …
Tarlatamab-dlle (Imdelltra) works by bringing healthy T cells (immune cells that help kill cancer cells) and lung cancer cells close together so the T cells can more effectively kill the lung cancer cells.
Aug 1, 2025 · Tarlatamab-dlle injection is used to treat extensive stage small cell lung cancer (ES-SCLC) that has spread throughout the lung or to other parts of the body in patients who have received other …
One promising BiTE is tarlatamab, also known as AMG 757 (9). This drug works by binding to delta-like ligand 3 (DLL3) on tumor cells and cluster of differentiation 3 (CD3) on T cells, which triggers T cell …
Tarlatamab-dlle is a bispecific T-cell engager that binds to DLL3 expressed on the surface of cells, including tumor cells, and CD3 expressed on the surface of T-cells.
Nov 30, 2023 · Tarlatamab, administered as a 10-mg dose every 2 weeks, showed antitumor activity with durable objective responses and promising survival outcomes in patients with previously treated small …
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